EP2 receptor agonists

US9309187B2 · kind B2 · utility

Assignee

• TAKEDA GMBH · DE

Inventors

• Angelika Hoffmeyer · Konstanz, DE
• Rainer Boer · Konstanz, DE
• Manuela Hessmann · Ahrensburg, DE
• Andreas Pahl · Ladenburg, DE
• Torsten Dunkern · Refrath, DE
• Simone Hartung · Allensbach, DE
• Christof Zitt · Konstanz, DE
• Jürgen Volz · Radolfzell, DE
• Christiane Praechter · Hamburg, DE
• Mahindra Makhija · Mumbai, IN
• Hiteshkumar D. Jain · Mumbai, IN
• Sandip Gavade · Ashti, IN
• Arati Prabhu · Mumbai, IN
• Manojkumar Tiwari · Jamkhed, IN
• Ashish Keche · Jamkhed, IN
• Sarvesh Patel · Jamkhed, IN

Key dates

• Filing date: Apr 30, 2013
• Grant date: Apr 12, 2016
• Expiry date: Apr 30, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/155
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The compounds of formula (1)in which R1, R4, A and X have the meanings as given in the description, are novel effective EP2 agonists.