Patent · US Active

Macrocyclic broad spectrum antibiotics

US9309285B2 · kind B2 · utility

5Cited by
2References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 21, 2013
Grant dateApr 12, 2016
Priority date
Expiry dateNov 21, 2033

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.