Patent · US Active

Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV

US9309506B2 · kind B2 · utility

0Cited by

2References

6Claims

0Family size

Assignee

Baxalta Incorporated · CH

Inventors

Bernhard Laemmle · Bolligen, CH
Helena Elisabeth Schaller-Gerritsen · Boswil, CH
Miha Furlan · Bern, CH
Peter Turecek · Klosterneuburg, AT
Hans-Peter Schwarz · Wien, AT
Friedrich Scheiflinger · Wien, AT
Gerhard Antoine · Groß-Enzersdorf, AT
Randolf Kerschbaumer · Klosterneuburg, AT
Luigina Tagliavacca · Milano, IT
Klaus Zimmermann · Wien, AT

Key dates

Filing date	Apr 7, 2014
Grant date	Apr 12, 2016
Priority date	—
Expiry date	Apr 7, 2034

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y304/24087
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to vWF cleaving entities having a molecular weight of 180 kD, 170 kD, 160 kD, 120 kD or 110 kD and an N-terminal amino acid sequence of AAGGILHLELLV, vWF cleaving complexes and methods for their production.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.