Molecular conjugate
US9310373B2 · kind B2 · utility
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47References
16Claims
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Key dates
| Filing date | Feb 14, 2014 |
| Grant date | Apr 12, 2016 |
| Priority date | — |
| Expiry date | Mar 8, 2034 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/535
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is disclosed for making a conjugate of two molecules using a hydrazide thiol linker. In a particular working embodiment, an Fc-specific antibody-enzyme conjugate is made using the method and demonstrated to provide exceptional staining sensitivity and specificity in immunohistochemical and in situ hybridization assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.