Nucleic acid delivery composition and carrier composition, pharmaceutical composition using the same, and method for nucleic acid delivery
US9314529B2 · kind B2 · utility
5Cited by
2References
8Claims
0Family size
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Key dates
| Filing date | Jul 11, 2011 |
| Grant date | Apr 19, 2016 |
| Priority date | — |
| Expiry date | Aug 28, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G63/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An excellent nucleic acid delivery composition is provided which has reduced cytotoxicity and improved nucleic acid introduction efficiency and gene expression efficiency. The composition comprises: a block copolymer having an uncharged hydrophilic polymer segment and a cationic polymer segment; a cationic polymer; and a nucleic acid, wherein the mol percentage (B/H ratio) of the cationic groups of the block copolymer to the total cationic groups of the block copolymer and the cationic polymer is between 25% and 90%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.