Patent · US Active

Nucleic acid molecules encoding antibody drug conjugates (ADC) that bind to 191P4D12 proteins

US9314538B2 · kind B2 · utility

8Cited by
14References
33Claims
0Family size

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Key dates

Filing dateJul 13, 2015
Grant dateApr 19, 2016
Priority date
Expiry dateJul 13, 2035

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2317/92
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.