Adsorption of immunopotentiators to insoluble metal salts
US9315530B2 · kind B2 · utility
5Cited by
16References
18Claims
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Key dates
| Filing date | Sep 1, 2011 |
| Grant date | Apr 19, 2016 |
| Priority date | — |
| Expiry date | Sep 16, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Immunopotentiators can be adsorbed to insoluble metal salts, such as aluminum salts, to modify their pharmacokinetics, pharmacodynamics, intramuscular retention time, and/or immunostimulatory effect. Immunopotentiators are modified to introduce a moiety, such as a phosphonate group, which can mediate adsorption. These modified compounds can retain or improve their in vivo immunological activity even when delivered in an adsorbed form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.