Human artificial chromosome vector
US9315824B2 · kind B2 · utility
5Cited by
5References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 2010 |
| Grant date | Apr 19, 2016 |
| Priority date | — |
| Expiry date | Apr 10, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/208
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a human artificial chromosome vector comprising a gene encoding the human antibody heavy chain, a gene encoding the human antibody light chain, and a gene encoding IgM heavy chain constant region derived from a nonhuman animal; and being capable of producing a human antibody with a higher efficiency when the vector is introduced into an animal. By immunizing the animal produced using a human artificial chromosome vector of the present invention with a desired antigen, a large quantity of human polyclonal antibodies can be supplied.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.