Patent · US Active

Methods for intracellular delivery of nucleic acids

US9315829B2 · kind B2 · utility

0Cited by
20References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 14, 2011
Grant dateApr 19, 2016
Priority date
Expiry dateJan 14, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2510/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for intracellular delivery of isolated naked nucleic acids into a biological tissue or organ, that includes (a) contacting the tissue or organ with an efficient amount of at least one active corticosteroid, and (b) contacting the tissue or organ treated in step b with an efficient amount of isolated naked nucleic acids, wherein step (a) is carried out for a period of time ranging from at least five minutes to at most two hours and being immediately followed by step (b).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.