Yeast cells expressing an exogenous cellulosome and methods of using the same
US9315833B2 · kind B2 · utility
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Key dates
| Filing date | Feb 18, 2010 |
| Grant date | Apr 19, 2016 |
| Priority date | — |
| Expiry date | Dec 5, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/52
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the engineering and expression of heterologous cellulosomes in microorganisms in order to facilitate the conversion of biomass to useful products. In some embodiments, the invention relates to the expression of scaffoldin proteins which form the nucleus of a cellulosome. Cellulases or other biomass-degrading enzymes can be non-covalently linked to the scaffoldin protein by virtue of a dockerin domain-cohesin domain interaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.