Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging
US9316645B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 5, 2012 |
| Grant date | Apr 19, 2016 |
| Priority date | — |
| Expiry date | Oct 5, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods, compositions, systems, devices and kits are provided herein for preparing and using a nanoparticle composition and spatial frequency heterodyne imaging for visualizing cells or tissues. In various embodiments, the nanoparticle composition includes at least one of: a nanoparticle, a polymer layer, and a binding agent, such that the polymer layer coats the nanoparticle and is for example a polyethylene glycol, a polyelectrolyte, an anionic polymer, or a cationic polymer, and such that the binding agent that specifically binds the cells or the tissue. Methods, compositions, systems, devices and kits are provided for identifying potential therapeutic agents in a model using the nanoparticle composition and spatial frequency heterodyne imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.