Substituted imidazopyridazines

US9320737B2 · kind B2 · utility

Assignee

• Bayer Intellectual Property GmbH · DE

Inventors

• Knut Eis · Berlin, DE
• Florian Puehler · Wellesley, US
• Ludwig Zorn · Berlin, DE
• Arne Scholz · Berlin, DE
• Philip Lienau · Berlin, DE
• Mark Jean Gnoth · Mettmann, DE
• Ulf Bömer · Glienicke, DE
• Judith Günther · Berlin, DE

Key dates

• Filing date: Sep 20, 2012
• Grant date: Apr 26, 2016
• Expiry date: Sep 20, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/048
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to substituted imidazopyridazine compounds of general formula (I): in which A, Q, R1, R3, R4 and n are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.