Nanoparticle comprising hydrophobic drug conjugated to cationic polymer and hydrophilic drug conjugated to anionic polymer
US9320809B2 · kind B2 · utility
1Cited by
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8Claims
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Key dates
| Filing date | Feb 24, 2015 |
| Grant date | Apr 26, 2016 |
| Priority date | — |
| Expiry date | Feb 24, 2035 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/911
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a nanoparticle including a hydrophobic drug conjugated to a cationic polymer and a hydrophilic drug conjugated to an anionic polymer, a method of preparing the same and a pharmaceutical use thereof. The nanoparticle according to an embodiment of the present invention may deliver the hydrophilic drug and the hydrophobic drug at the same time, and may control an initial drug burst. Further, the nanoparticle according to an embodiment of the present invention is specific to a cancer cell environment, and thus selective diagnosis or treatment of cancer cells is possible.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.