Therapy targeting cathepsin S
US9321838B2 · kind B2 · utility
0Cited by
8References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 10, 2007 |
| Grant date | Apr 26, 2016 |
| Priority date | — |
| Expiry date | Jul 9, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a method of inhibiting chemotherapy induced upregulation of Cathepsin S on the surface of tumor cells, the method comprising the administration of a Cathepsin S inhibitor to said cells. Also provided is a therapy comprising an anti Cathepsin S antibody, in particular an anti-Cathepsin S antibody which does not inhibit the proteolytic effect of Cathepsin S but nevertheless inhibits angiogenesis and a combination treatment comprising a Cathepsin S inhibitor and a therapeutic agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.