Tissue modeling in embryonic stem (ES) cell system

US9321997B2 · kind B2 · utility

Assignee

• AXIOGENESIS AG · DE

Inventors

• Eugen Kolossov
• Jürgen Hescheler · Cologne, DE
• Heribert Bohlen · Cologne, DE
• Bernd Fleischmann · Bonn, DE
• Wilhelm Röll · Bonn, DE
• Andreas Ehlich · Mechernich, DE
• Jessica Königsmann · Berlin, DE

Key dates

• Filing date: Jun 21, 2004
• Grant date: Apr 26, 2016
• Expiry date: May 12, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2800/52
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are embryonic stem (ES) cell-derived tissue modeling systems. In particular, systems for the de novo generation of tissue by parallel drug selection of cell types constituting the tissue of interest in one culture of differentiating ES cells is described as well as the use of such systems in transplantation and drug development.