Patent · US Active

Hydroxymethyl linkers for labeling nucleotides

US9322050B2 · kind B2 · utility

2Cited by
16References
5Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJul 25, 2013
Grant dateApr 26, 2016
Priority date—
Expiry dateFeb 11, 2034

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6806
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.