Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
US9326953B2 · kind B2 · utility
3Cited by
45References
15Claims
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Key dates
| Filing date | Nov 9, 2012 |
| Grant date | May 3, 2016 |
| Priority date | — |
| Expiry date | Nov 9, 2032 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/907
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A system and method for optimizing the systemic delivery of growth-arresting lipid-derived bioactive drugs or gene therapy agents to an animal or human in need of such agents utilizing nanoscale assembly systems, such as liposomes, resorbable and non-aggregating nanoparticle dispersions, metal or semiconductor nanoparticles, or polymeric materials such as dendrimers or hydrogels, each of which exhibit improved lipid solubility, cell permeability, an increased circulation half life and pharmacokinetic profile with improved tumor or vascular targeting.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.