Method for high-throughput screening of drops by osmotic exchange and density variation

US9327242B2 · kind B2 · utility

Assignees

• CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE · FR
• Universite Pierre Et Marie Curie (Paris 6) · FR
• Ecole Normale Superieure de Lyon Lyon · FR
• UNIVERSITÉ PARIS DIDEROT—PARIS 7 · FR

Inventors

• Gaël Yvert · Saint-Genis-Laval, FR
• Jerome Bibette · Bordeaux, FR
• Jean Baudry · Paris, FR
• Laurent Boitard · Paris, FR
• Nicolas Bremond · Paris, FR
• Denis Cottinet · Paris, FR

Key dates

• Filing date: Mar 21, 2012
• Grant date: May 3, 2016
• Expiry date: Jan 21, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2015/1028
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

This method comprises bringing drops to be separated into contact with an interface (40) suitable for allowing an osmotic equilibrium between the content of each drop to be separated. The method comprises an osmotic flow between the drops (20A) of the first group of drops through the interface (40) in order to modify the density of each drop (20A) of the first group of drops and the separation of the drops (20A, 20B) according to the density thereof or a combination of the density and the volume in order to isolate the drops (20A) of the first group of drops from the drops (20B) of a second group of drops.