Substituted cycloocta[5,6]pyrido[4,3,2-de]phthalazines as PARP inhibitors
US9328111B2 · kind B2 · utility
101Cited by
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6Claims
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Key dates
| Filing date | Dec 31, 2011 |
| Grant date | May 3, 2016 |
| Priority date | — |
| Expiry date | Dec 31, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a compound of Formula (I):wherein the variables Z, n, Y and p are as defined herein, and pharmaceutically acceptable salts thereof, which can inhibit the activity of poly (ADP-ribose)polymerases, and pharmaceutical compositions comprising the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.