Patent · US Active

Use of chimeric antigen receptor-modified T cells to treat cancer

US9328156B2 · kind B2 · utility

78Cited by
27References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 16, 2013
Grant dateMay 3, 2016
Priority date
Expiry dateDec 16, 2033

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2740/15071
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.