Self-contained biological assay apparatus, methods, and applications

US9328381B2 · kind B2 · utility

Assignee

• Rheonix, Inc. · US

Inventors

• Peng Zhou · Newtown, US
• Lincoln C. Young · Ithaca, US
• Benjamin Thomas · Freeville, US
• Zongyuan Chen · Westtown, US
• Todd Roswech · Westbrook, US
• Gwendolyn Spizz · Ithaca, US
• Rubina Yasmin · Ithaca, US
• Greg Mouchka · Brooktondale, US

Key dates

• Filing date: Jul 14, 2015
• Grant date: May 3, 2016
• Expiry date: Jul 14, 2035

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2035/00346
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A self-contained, fully automated, biological assay-performing apparatus includes a housing; a dispensing platform including a controllably-movable reagent dispensing system, disposed in the housing; a reagent supply component disposed in the housing; a pneumatic manifold removably disposed in the housing in a space shared by the dispensing platform, removably coupled to a fluidic transport layer and a plurality of reservoirs, wherein the fluidic transport layer, the reservoirs, and a test sample to be introduced therein are disposed in the housing in the space separate from the dispensing platform; a pneumatic supply system removably coupled to the pneumatic manifold in the housing in a space separate from the dispensing platform; and a control system coupled to at least one of the dispensing platform and the pneumatic supply system, disposed in the housing.