Use of simple amino acids to form porous particles
US9333174B2 · kind B2 · utility
12Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2012 |
| Grant date | May 10, 2016 |
| Priority date | — |
| Expiry date | Dec 24, 2034 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/183
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Particles having a tap density of less than 0.4 g/cm3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred particles include a phospholipid, have a median geometric diameter between about 5 and about 30 microns and an aerodynamic diameter between about 1 and about 5 microns. The particles can be formed by spray-drying and are useful for delivery to the pulmonary system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.