Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease

US9333202B2 · kind B2 · utility

Assignee

• The Trustees of Columbia University in the City of New York · US

Inventors

• Konstantin Petrukhin · Collegeville, US
• Janet R. Sparrow · New York, US
• Rando Allikmets · Frederick, US

Key dates

• Filing date: Apr 30, 2013
• Grant date: May 10, 2016
• Expiry date: Apr 30, 2033

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/519
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for treating a disease characterized by excessive lipofuscin accumulation in the retina in mammals afflicted therewith, comprising administering to the mammal an effective amount of a non-retinoid antagonist compound or a pharmaceutically acceptable salt thereof.