Bone/polyurethane composites and methods thereof
US9333276B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 29, 2009 |
| Grant date | May 10, 2016 |
| Priority date | — |
| Expiry date | Jan 22, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Present inventions present composites of bone particles and polyurethane(s), as well as methods of making such composite and uses thereof. A porous composite comprises a plurality of bone particles; and polyurethanes with which the bone particles are combined. To prepare a porous composite, a composition comprise a plurality of bone particles, polyurethane precursors including polyisocyanate prepolymers and polyols, water and catalyst. A composition is either naturally moldable and/or injectable, or it can be made moldable and/or injectable. After implantation or injection, a composition may be set to form a porous composite that provides mechanical strength and supports the in-growth of cells. Inventive composites have the advantage of being able to fill irregularly shape implantation site while at the same time being settable to provide the mechanical strength for most orthopedic applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.