Process for preparing sulfonamidobenzofuran derivatives
US9334254B2 · kind B2 · utility
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29References
10Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 30, 2011 |
| Grant date | May 10, 2016 |
| Priority date | — |
| Expiry date | Mar 30, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/79
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for preparing 5-sulfonamido-benzofuran derivatives of general formula: formula (I) in which R represents an alkyl or aryl group and R1 and R2 represent hydrogen or an alkyl or aryl group. According to the invention, the compounds of formula I are prepared by coupling a benzofuran derivative of general formula II, where X represents chlorine, bromine or iodine or a sulfonate group: formula (II) with a sulfonamide derivative of formula R—SO2—NH2, in the presence of a basic agent and of a catalyst system formed from a complex between a palladium compound and a ligand.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.