Water-soluble camptothecin derivative, pharmaceutical composition and use thereof
US9334299B2 · kind B2 · utility
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0References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 27, 2011 |
| Grant date | May 10, 2016 |
| Priority date | — |
| Expiry date | Dec 13, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/207
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a water soluble derivative of camptothecin and preparation method thereof, the derivative having a structure of formula I and being appropriate in water solubility, and having anti-cancer activity and stability of lactonic ring. The present invention also relates to a method for synthesizing the compound and medical use of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.