Methods of antagonizing signal transduction in spinal cord cells using an IL-31Ra or OSMR-b antagonist
US9334322B2 · kind B2 · utility
3Cited by
26References
4Claims
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Key dates
| Filing date | Jan 27, 2015 |
| Grant date | May 10, 2016 |
| Priority date | — |
| Expiry date | Jan 27, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Use of antagonists to IL-31Ra and OSMRb are used to treat inflammation and pain by inhibiting, preventing, reducing, minimizing, limiting or minimizing stimulation in neuronal tissues. Such antagonists include soluble receptors, antibodies and fragments, derivative, or variants thereof. Symptoms such as pain, tingle, sensitization, tickle associated with neuropathies are ameliorated.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.