Patent · US Active

Micronized opioid compositions having a specific particle size distribution

US9339463B2 · kind B2 · utility

0Cited by

1References

29Claims

0Family size

Inventors

Michael Zamloot · Austin, US
Cherng-Chyi Fu · Saratoga, US
De-Hwa Chao · Cupertino, US
Andrei Blasko · San Bruno, US
Su Il Yum · Los Altos, US

Key dates

Filing date	Dec 5, 2008
Grant date	May 17, 2016
Priority date	—
Expiry date	Jun 12, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel compositions, formulations and dosage forms comprising stabilized micronized opioid particles are disclosed. Exemplary opioids include oxycodone, oxymorphone, hydrocodone, and hydromorphone, including as free bases or as salts. Stabilized micronized opioid particles having a Dv90 particle size distribution of less and or equal to 10μ or less than or equal to 20μ are disclosed. Methods for micronizing an opioid to provide stabilized micronized opioid particles are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.