Pyrazolone-derivatives and their use as PDE-4 inhibitors

US9340522B2 · kind B2 · utility

Assignee

• TAKEDA GMBH · DE

Inventors

• Imre Schlemminger · Konstanz, DE
• Beate Schmidt · Allensbach, DE
• Dieter Flockerzi · Allensbach, DE
• Hermann Tenor · Konstanz, DE
• Christof Zitt · Konstanz, DE
• Armin Hatzelmann · Konstanz, DE
• Degenhard Marx · Radebeul, DE
• Clemens Braun · Konstanz, DE
• Raimund Kuelzer · Mittelbiberach, DE
• Anke Heuser · Hamburg, DE
• Hans-Peter Kley · Allensbach, DE
• Geert Jan Sterk · Utrecht, NL

Key dates

• Filing date: Nov 15, 2013
• Grant date: May 17, 2016
• Expiry date: May 10, 2034

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The compounds of Formula (I),are novel effective inhibitors of the type 4 phosphodiesterase.