Oxazolidinone compounds and derivatives thereof

US9340549B2 · kind B2 · utility

Assignee

• AMGEN INC. · US

Inventors

• Howard Bregman · Melrose, US
• John L. Buchanan · Brookline, US
• Nagasree Chakka · Waltham, US
• Erin F. Dimauro · Cambridge, US
• Hakan Gunaydin · Boston, US
• Angel Guzman-Perez · Belmont, US
• Zihao Hua · Andover, US
• Hongbing Huang · Watertown, US
• Xin Huang · Brookline, US
• Matthew W. Martin · Arlington, US
• Vinod F. Patel · Acton, US

Key dates

• Filing date: Mar 1, 2013
• Grant date: May 17, 2016
• Expiry date: Mar 1, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D519/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of Formula (I) and Formula (II) are useful inhibitors of tankyrase. Compounds of Formula (I) and Formula (II) have the following structure: where the definitions of the variables are provided herein.