Chromatographic material and method for preparation thereof
US9340562B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Oct 29, 2014 |
| Grant date | May 17, 2016 |
| Priority date | — |
| Expiry date | Oct 29, 2034 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/305
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A chromatographic material comprising a zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II:whereinR1, R2, R3 are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group;L1, L2 and L3 are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L1, L2 and L3;X is an O atom, S atom, amide group or sulfonamide group;n is 0 or 1;R4, R5 are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; andRf is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.