Patent · US Active

Mass labels

US9341635B2 · kind B2 · utility

0Cited by

3References

5Claims

0Family size

Assignee

ELECTROPHORETICS LIMITED · GB

Inventors

Christian Baumann · Sangerhausen, DE
Stefan Kienle · Frankfurt, DE
Karsten Kuhn · Dortmund, DE
Harald Legner · Frankfurt am Main, DE

Key dates

Filing date	Sep 8, 2010
Grant date	May 17, 2016
Priority date	—
Expiry date	Sep 8, 2030

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/24
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A reactive mass label for labelling a biological molecule for detection by mass spectrometry, which label comprises a reactive functionality for labelling thiol groups or carbonyl groups. Also provided is a reactive mass label for labelling a biological molecule for detection by mass spectrometry, wherein the mass label comprises the following structure:X-L-M-S—Rewherein X is a mass marker moiety, L is a cleavable linker, M is a mass normalization moiety, S is a mass series modifying group comprising the following group:wherein J is C═O, K is NH, and n is 2 or J and K are both CH2 and n is 1, and wherein m is at least 1; and Re is a reactive functionality for attaching the mass label to a biological molecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.