Oil-in-water emulsion composition and method for producing the same
US9345651B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 24, 2012 |
| Grant date | May 24, 2016 |
| Priority date | — |
| Expiry date | Feb 23, 2032 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/21
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is an oil-in-water type emulsion composition containing a physiologically acceptable salt of a tranexamate ester and a method for producing the same. An oil-in-water type emulsion composition containing a physiologically acceptable salt of a tranexamate ester can be obtained by preparing an oil phase including: A) a physiologically acceptable salt of a tranexamate ester; B) an amphiphilic substance; C) an oily substance; and D) water, a water-soluble organic solvent or a mixture thereof wherein the weight ratio of the ingredients A:B is in the range of 1:0.5 to 1:2.5, the weight ratio of the ingredients A:C is in the range of 1:1 to 1:5.0, and the weight ratio of the ingredients A:D is 1:0.2 to 1:5.0, and adding the oil phase to a water phase including E) water, a water-soluble organic solvent or a mixture thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.