Allogeneic tumor therapeutic agent, a vaccine using allogeneic tumor cells for the therapeutic treatment of tumor diseases, and a method for the making of such a vaccine, and transfected human tumor cells for use as a vaccine

US9345754B2 · kind B2 · utility

Assignee

• Mologen AG · DE

Inventors

• Tomislav Dobric · Berlin, DE
• Burghardt Wittig · Berlin, DE
• Manuel Schmidt · Berlin, DE

Key dates

• Filing date: Nov 9, 2009
• Grant date: May 24, 2016
• Expiry date: May 27, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2510/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A vaccine on the basis of allogeneic tumor cells for the therapeutic treatment of defined tumor diseases, and a method for the making of such vaccine is disclosed. The tumor cells were previously transfected ex vivo with expression constructs encoding cytokines and co-stimulatory factors.