Patent · US Active

Compounds for binding to the platelet specific glycoprotein IIB/IIIA and their use for imaging of thrombi

US9345793B2 · kind B2 · utility

0Cited by

3References

15Claims

0Family size

Assignee

PIRAMAL IMAGING SA · CH

Inventors

Markus Berger · Berlin, DE
Martin Kruger · Berlin, DE
Jessica Lohrke · Berlin, DE
Michael Reinhardt · Mannheim, DE
Holger Siebeneicher · Berlin, DE

Key dates

Filing date	Aug 17, 2012
Grant date	May 24, 2016
Priority date	—
Expiry date	Dec 16, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K5/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (PET) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body. More particularly, the invention relates to small nonpeptide, high-affinity, specific-binding glycoprotein 11b/IIIa antagonists for imaging of thrombi.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.