Patent · US Active

Polyamine transport selective therapeutic agents with enhanced stability

US9346741B2 · kind B2 · utility

3Cited by

1References

17Claims

0Family size

Assignee

University of Central Florida Research Foundation · US

Inventors

Otto Phanstiel · Oviedo, US
Aaron Muth · Orlando, US

Key dates

Filing date	Mar 14, 2013
Grant date	May 24, 2016
Priority date	—
Expiry date	Mar 14, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08G73/0206
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Disclosed herein are di-substituted aryl polyamine compounds and methods of making and using the same. The di-substituted polyamine compounds act as PTS targeting agents, which selectively target the polyamine transport system (PTS) with high efficacy and have improved stability in the presence of amine oxidases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.