Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
US9346799B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Oct 13, 2014 |
| Grant date | May 24, 2016 |
| Priority date | — |
| Expiry date | Oct 13, 2034 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition, comprising a combination of an antibiotically active compound of the formula (I): with a β-lactamase inhibitor of one of the formulae (II) to (XIII) are active against Gram-negative bacteria, in particular such bacteria which have become resistant against antibiotics such as aztreonam, carumonam and tigemonam. Optionally the compositions may comprise another β-lactamase inhibitor of one of the formulae (II) to (XIII), particularly of formula (V) or formula (VI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.