Detection and use of low molecular-weight modulators of the cold-menthol receptor TRPM8

US9346823B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Thomas Subkowski · Schriesheim, DE
• Claus Bollschweiler · Heidelberg, DE
• Jens Wittenberg · Schifferstadt, DE
• Michael Krohn · Lorsch, DE
• Holger Zinke · Zwingenberg, DE

Key dates

• Filing date: Mar 12, 2014
• Grant date: May 24, 2016
• Expiry date: Mar 12, 2034

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/78
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to novel modulators of the cold menthol receptor TRPM8, to a method for modulating the TRPM8 receptor using said modulators; to the use of the modulators for induction of cold sensation; and to objects and means produced using said modulators.