Patent · US Active

Reprogramming T cells and hematopoietic cells

US9347044B2 · kind B2 · utility

8Cited by
1References
41Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 22, 2014
Grant dateMay 24, 2016
Priority date
Expiry dateApr 22, 2034

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02E60/10
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.