Method for filtering a chromatogram

US9347921B2 · kind B2 · utility

Assignee

• Siemens Aktiengesellschaft · DE

Inventor

• Frank Probst · Landau in der Pfalz, DE

Key dates

• Filing date: Jul 29, 2010
• Grant date: May 24, 2016
• Expiry date: Mar 28, 2033

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N30/8693
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Low-complexity, application-independent fixation of a chromatogram is achieved by a) determining a limit frequency under the assumption that the shape of the peaks in the chromatogram corresponds approximately to a Gaussian function having a standard deviation and the Fourier transform of the Gaussian function describes the frequency spectrum of a peak, at which limit frequency the Fourier transform has decreased to a predetermined limit value, b) determining the height, width, and retention time of each individual peak from the chromatogram, or a chromatogram taken previously under the same conditions, c) determining a constant factor based on a first predetermined relationship, d) determining the functional dependency of the limit frequency on the retention time as a variable quantity based on a second predetermined relationship, and e) filtering the chromatogram with the limit frequency depending on the retention time as the variable quantity using a low-pass filter.