Patent · US Active

Double cross-linkage process to enhance post-implantation bioprosthetic tissue durability

US9351829B2 · kind B2 · utility

1Cited by

232References

25Claims

0Family size

Assignee

EDWARDS LIFESCIENCES CORPORATION · US

Inventors

Sophie Carpentier · Paris, FR
Alain F. Carpentier · Paris, FR

Key dates

Filing date	Nov 15, 2011
Grant date	May 31, 2016
Priority date	—
Expiry date	Nov 15, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61L2430/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Bioprosthetic tissues and methods for making same, comprising fixing bioprosthetic implant tissue by treatment with 0.1 to 10 wt. % glutaraldehyde at elevated temperature, capping said fixed tissue by treatment with a diamine crosslinking agent, and treating said capped tissue with about 0.6 wt. % glutaraldehyde.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.