Super-oxide dismutase mimetics
US9353069B2 · kind B2 · utility
2Cited by
5References
21Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 12, 2013 |
| Grant date | May 31, 2016 |
| Priority date | — |
| Expiry date | Mar 6, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds which are effective as catalysts for dismutating superoxide and, more particularly, the manganese or iron complexes of substituted, unsaturated heterocyclic 16-membered macrocyclic complexes that catalytically dismutate superoxide. It also relates to methods of using these complexes to reduce the concentration or the effects of superoxide, pharmaceutical compositions comprising these compounds or their metal complexes, and methods of treating conditions associated with excessive superoxide activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.