Inhibitors of Bruton's tyrosine kinase

US9353087B2 · kind B2 · utility

Assignees

• Biogen MA Inc. · US
• Sunesis Pharmaceuticals, Inc. · US

Inventors

• Brian T. Hopkins · Newton, US
• Xiongwei Cai · Arlington, US
• Timothy Chan · Cambridge, US
• Patrick R. Conlon · Wakefield, US
• Michael Humora · Weston, US
• Tracy J. Jenkins · Watertown, US
• Michael MacPhee · Central Falls, US
• Xianglin Shi · Newton, US
• Ross A. Miller · Fanwood, US
• Andrew Thompson

Key dates

• Filing date: Jun 7, 2013
• Grant date: May 31, 2016
• Expiry date: Jun 7, 2033

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides a compound, solid forms, and compositions thereof, which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same. The present invention also provides methods of making provided compound and solid forms.