Synthesis and use of croconaine compounds
US9353092B2 · kind B2 · utility
1Cited by
5References
20Claims
0Family size
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Inventor
Key dates
| Filing date | Jun 21, 2014 |
| Grant date | May 31, 2016 |
| Priority date | — |
| Expiry date | Jun 21, 2034 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure provides compositions and methods for the synthesis and use of croconaine compounds. The disclosed compounds are easily prepared from croconic acid. A halothiophene is reacted with an alkanolamine, the resulting aminothiophene is modified by appending a desired functional group to the hydroxyl group, and the modified aminothiophene is reacted with croconic acid to form the final compound. Applications of such croconaine compounds include photothermal imaging, photothermal therapy, light-activated drug release, and tissue welding.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.