Breath condensate sampler and detector and breath/breath condensate sampler and detector
US9357946B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 2010 |
| Grant date | Jun 7, 2016 |
| Priority date | — |
| Expiry date | Apr 2, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2001/2282
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a direct sampler and detector for analytes found in exhaled breath condensate. Analytes in the breath condensate are detected instantaneously as they condense prior to reaching the sensor surface or condense directly on the sensor surface. Because the analysis or assay is performed immediately after patient exhalation, analyte stability is significantly improved providing accurate, reliable, consistent, and clinically applicable results. In certain embodiments, combined breath condensate/breath samplers and detectors are provided, enabling multiplexed analysis of condensed and vapor-phase analytes provided in a single sampling session. Breath is collected and directed to one or more subsystems. Within each subsystem, the breath portion is either condensed or prevented from condensing. The technique also allows real-time continuous monitoring, thus allowing immediate feedback to both medical professionals and additional hardware such as ventilators, anesthesia machines, drug infusion systems and cardiac pacemakers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.