Use of Pateamine A for the treatment of age-related muscle wasting
US9358249B2 · kind B2 · utility
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3Claims
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Key dates
| Filing date | Nov 18, 2009 |
| Grant date | Jun 7, 2016 |
| Priority date | — |
| Expiry date | Nov 18, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
In certain embodiments this invention pertains to the discovery that inhibition of the expression and/or activity of eukaryotic initiation factor 4A (eIF4A) inhibits the aging process. Accordingly, in certain embodiments, methods are provided for inhibiting/slowing aging. The methods typically involve administering to a mammal an agent that inhibits the expression and/or activity of eukaryotic initiation factor 4A (eIF4A) in an amount sufficient to inhibit expression or activity of EIF4A, where the agent is not resveratrol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.