Identification of compounds that disperse TDP-43 inclusions
US9359363B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | May 21, 2012 |
| Grant date | Jun 7, 2016 |
| Priority date | — |
| Expiry date | Aug 5, 2032 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5058
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Herein, methods of modulating inclusion formation and stress granules in cells are described. The methods comprise contacting a cell with an inclusion inhibitor. Methods for screening for modulators of TDP-43 aggregation are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.