Patent · US Active

Method for purifying GLA-domain coagulation proteins

US9359610B2 · kind B2 · utility

1Cited by

0References

14Claims

0Family size

Assignee

Laboratoire Francais du Fractionnement et des Biotechnologies · FR

Inventors

Gerald Perret · Paris, FR
Sami Chtourou · Élancourt, FR
Nicolas Bihoreau · Orsay, FR

Key dates

Filing date	Jul 30, 2010
Grant date	Jun 7, 2016
Priority date	—
Expiry date	Jan 22, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2330/31
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for purifying GLA-domain coagulation proteins, includes the following steps: a) bringing a sample containing one or more GLA-domain coagulation proteins into contact with an affinity substrate on which nucleic aptamers which bind specifically to the GLA-domain coagulation proteins are immobilized, in order to form complexes between (i) the nucleic aptamers and (ii) the GLA-domain coagulation protein(s), b) releasing the GLA-domain coagulation protein(s) from the complexes formed in step a), and c) recovering the GLA-domain coagulation protein(s) in a purified form.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.