Patent · US Active

Twin-focus photothermal correlation spectroscopy method and device for the characterization of dynamical processes in liquids and biomaterials with the help of absorbing markers

US9360416B2 · kind B2 · utility

0Cited by

5References

11Claims

0Family size

Assignee

UNIVERSITÄT LEIPZIG · DE

Inventors

Frank Cichos · Berlin, DE
Marco Braun · Bukit Mertajam, MY
Markus Selmke · Leipzig, DE
Romy Schachoff · Leipzig, DE

Key dates

Filing date	Jul 12, 2012
Grant date	Jun 7, 2016
Priority date	—
Expiry date	Sep 22, 2032

Classification

Technology area (CPC G)Physics
CPC primaryG01N2021/1789
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention relates to a method and a device for twin-focus photothermal correlation spectroscopy for the characterization of dynamical processes in liquids and biomaterials with the help of absorbing markers. Thereby non-fluorescent absorbing nano objects are heated by an intensity-modulated heating laser which leads to a refractive index gradient lens around the object. This refractive index gradient is detected by a detection laser with a focal volume that, depending on the position of the heated object relative to the focal plane of the detection beam, splits into two-sub-volumes forming a twin-focus comprising two sharply separated parts of a focal volume showing no spatial overlap.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.