Method and apparatus for the assessment of medical images

US9361686B2 · kind B2 · utility

Assignee

• COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION · AU

Inventors

• Vincent Dore · Paris, FR
• Olivier Salvado · Thorigny, FR
• Nicholas Dowson · North Hinksey, GB
• Jurgen Mejan-Fripp · Brisbane, AU
• Christopher Rowe · Armidale, AU
• Victor Villemagne · Melbourne, AU
• Luping Zhou · Forbes, AU

Key dates

• Filing date: Dec 14, 2012
• Grant date: Jun 7, 2016
• Expiry date: Dec 14, 2032

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30016
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method of determining the degree of uptake of a PET maker in an individual candidate PET scan, the method including the steps of: (a) calculating a series of representative matched controlled PET and MRI templates for a series of controlled sample scans of individuals; (b) computing a series of brain surfaces from the matched templates; (c) aligning the individual candidate PET scan with the candidate templates; (d) aligning the candidate PET images with the series of brain surfaces; (e) selecting a predetermined (M) best candidate templates for each surface location based on a similarity measure between the candidate PET values and the corresponding controlled PET scans; (f) computing M weights for each surface location, utilizing a corresponding MRI tissue map; (g) utilizing the M weights to combine a corresponding M template tissue indicators from corresponding MRI templates into an average brain surface indicator.